Tetraspanin CD63 acts as a pro-metastatic factorviaβ-catenin stabilization
نویسندگان
چکیده
منابع مشابه
Regulation of Zebrafish Hatching by Tetraspanin cd63
Tetraspanins cause the clustering of membrane proteins into a level of organisation essential for cellular function. Given the importance and complicated nature of this mechanism, we attempted a novel approach to identify the function of a single component in a biologically relevant context. A morpholino knockdown strategy was used to investigate the role of cd63, a membrane protein associated ...
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Targeting mechanisms of neutrophil elastase (NE) and other luminal proteins stored in myeloperoxidase (MPO)-positive secretory lysosomes/primary granules of neutrophils are unknown. These granules contain an integral membrane protein, CD63, with an adaptor protein-3-dependent granule delivery system. Therefore, we hypothesized that CD63 cooperates in granule delivery of the precursor of NE (pro...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2014
ISSN: 0020-7136
DOI: 10.1002/ijc.29296